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Context-driven Infection Control Interventions

(CoDe-ICI)

 

CoDe-ICI is a project funded by Oxford-Berlin University Alliance with seed funding until December 2023. The overall aim of the project is to develop a long-lasting collaborative network of LMIC hospitals with a general focus on Africa and Asia and to tailor targeted high quality infection control intervention studies and campaign strategies in LMIC settings for which we will seek further funding.

There is an urgent need to develop the evidence base for effective interventions to combat health care associated infections (HAIs) and antimicrobial resistance (AMR) in low resource settings.

Infection prevention and control (IPC)

Few high quality infection prevention and control (IPC) intervention trials have been conducted inhospitals in low resource settings where the burden of antimicrobial resistance is greatest.

Hospitals face challenges

Hospitals in low resource settings often face challenges including limited financial and human resources, high
levels of patient crowding, limited antibiotic formularies, lack of infrastructure, and incentives for
antibiotic prescribing that may not always align with patient interests.

High-Income vs. Low-Resource Settings

These factors may impact the extent to which findings from high income settings can be generalised to LRS. The different economic circumstances will often mean that interventions which are routinely used in high income countries,
such as screening and isolation/decontamination of pathogens, are rarely used in LRS while others, such as expensive modifications to sinks to reduce their potential as reservoirs for infections, are of llittle relevance.

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The CoDe-ICI response

The aim of the project is to develop a collaborative network of hospitals partners and to tailortarget intervention studies in low resource settings.

This project will
leverage the platform of collaborators to develop infrastructure and tools to enhance patient safety, promote the corecomponents of IPC programmes, and advance initiatives of global surveillance of antimicrobialresistance, with a special focus on in low resource settings.

Video introduction
The CoDe-ICI project

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